2026-06-26
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anvino
Based on the donor's hormone levels (AMH/FSH), the physician designs a personalized stimulation protocol. Through injections of gonadotropins, multiple antral follicles in the ovaries are stimulated to mature simultaneously. This process typically lasts 10–12 days, with repeated ultrasound monitoring to track follicle size.
Once the follicles reach maturity, the physician performs a painless egg retrieval procedure. In the laboratory, embryologists use micromanipulation techniques to inject a single selected healthy sperm directly into the cytoplasm of the egg — known as ICSI (Intracytoplasmic Sperm Injection). This technique maximizes fertilization rates, particularly in cases involving suboptimal sperm quality.
Fertilized eggs are cultured in a specialized culture medium until Day 5 or Day 6, developing into a blastocyst — a structure composed of over 100 cells. At this stage, the embryo's structure is stable, and its implantation potential is significantly higher than that of an early Day 3 embryo.
This is the most critical step. The physician regulates the surrogate mother's endometrium using exogenous estrogen and progesterone, aiming for a thickness of 8–12mm — the clinical "gold standard." The team precisely identifies the implantation window before performing a frozen embryo transfer (FET), giving the embryo the best chance to implant successfully.
Q: Is ovarian stimulation harmful to the donor's health?
A: Under proper medical supervision, ovarian stimulation is safe. Physicians strictly control medication dosages to prevent Ovarian Hyperstimulation Syndrome (OHSS). Hormone levels in donors typically return to normal after their next menstrual cycle.
Q: What happens if the first embryo transfer is unsuccessful?
A: For clients on ANVINO's comprehensive program, multiple transfer attempts are included. If the first transfer is unsuccessful, our medical team re-evaluates the surrogate's uterine environment and schedules a subsequent transfer until a successful pregnancy is achieved.
Q: Do I need to be physically present for these procedures?
A: In most cases, no. Aside from sperm collection (which can be done on-site or via frozen sample shipment), the stimulation, culture, and transfer stages are all carried out by the medical team and surrogate abroad. You can safely await your pregnancy confirmation report.
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