Advanced Maternal Age (42y) Case: Micro-Stimulation Protocol & Clinical Pregnancy

Date2025-12-05 Views147 Authoranvino

📂 Case File
Client: Mrs. Zhang & Husband (Beijing, Age 42)
Challenge: Extremely Low Ovarian Reserve (AMH 0.6), Only 3 Antral Follicles
Solution: Micro-Stimulation IVF + PGT-A + Legal Surrogacy in Georgia
Result: 2 Retrieval Cycles, 3 Euploid Blastocysts, Success on 1st Transfer

"As Long as There is One Egg, I Want to Try for My Own"

"Doctors advised me to use a donor, but I couldn't get over that mental hurdle." When 42-year-old Mrs. Zhang consulted Anvino, her eyes were filled with both determination and anxiety.
Detailed tests revealed her AMH was only 0.6, and her FSH had soared to 18. This meant her ovarian function was on the "edge of a cliff," and every ovulation could be her last chance.

Facing such severe data, the Anvino medical expert team did not reject her. Instead, we proposed a tailored solution: "Self-Egg Micro-Stimulation + Surrogacy Support." We didn't chase the quantity of eggs, but the quality. As long as we could create one good embryo, there was hope.

Anvino experts designing a custom micro-stimulation plan for Mrs. Zhang

158 Days of Persistence: From Retrieval to Transfer

To seize her final fertility window, Mrs. Zhang began her journey of intensive travel and treatment.

  • Cycle 1: Using a gentle micro-stimulation protocol, 2 eggs were retrieved, resulting in 1 blastocyst.
  • Cycle 2: With an adjusted medication plan, 3 eggs were retrieved, resulting in 2 blastocysts.
  • PGT-A Screening: All 3 precious blastocysts were tested. The result was a medical miracle for a 42-year-old: 2 completely healthy (Euploid) male embryos!

Simultaneously, the Anvino team in Georgia matched her with a "Gold Standard" surrogate: 26 years old, with a history of one healthy natural delivery. After endometrial preparation, the surrogate's lining reached a perfect 9.5mm.

Day 12 Post-Transfer: Perfect HCG doubling confirmed

Continuing the Bloodline: Finally, You Are Here

The transfer surgery went smoothly. On Day 12, the blood test showed an HCG level of 680! Success on the very first try!
Throughout the pregnancy, Mrs. Zhang watched her baby grow in the surrogate's womb day by day via Anvino's video updates.

Ten months later, in a private hospital delivery room in Tbilisi, Mrs. Zhang held her biological son for the first time. In that moment, all the injections, medications, and travel turned into tears of joy.
"Thank you for not giving up on me, for letting me have a child of my own."


Your ovarian reserve may be low, but as long as there is a glimmer of hope, we will go all out.

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